BDBM50594890 CHEMBL5205796

SMILES CN(C)CCCOc1ncc(cc1NS(=O)(=O)C(F)(F)F)-c1ccc2ncc3N(C)C(=O)C4(CCC4)c3c2c1

InChI Key InChIKey=WEEIJHAKEWVFES-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50594890   

TargetDNA-dependent protein kinase catalytic subunit(Human)
Hubei Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50594890(CHEMBL5205796)
Affinity DataIC50: 1nMAssay Description:Inhibition of full-length human DNA-PK expressed in baculovirus expression system using p53 as substrate incubated for 1 hr in presence of ATP by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Hubei Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50594890(CHEMBL5205796)
Affinity DataIC50: 1nMAssay Description:Inhibition of ATM in human MCF7 cells using etoposide as substrate incubated for 1 hr by Cell Western assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed