BDBM50594889 CHEMBL5175568

SMILES CCc1ncc(s1)S(=O)(=O)Nc1cc(cnc1OCCCN(C)C)-c1ccc2ncc3N(C)C(=O)C4(CCC4)c3c2c1

InChI Key InChIKey=UNETUVMFOUXHNZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50594889   

TargetDNA-dependent protein kinase catalytic subunit(Human)
Hubei Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50594889(CHEMBL5175568)
Affinity DataIC50: 1nMAssay Description:Inhibition of full-length human DNA-PK expressed in baculovirus expression system using p53 as substrate incubated for 1 hr in presence of ATP by ELI...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSerine-protein kinase ATM(Human)
Hubei Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50594889(CHEMBL5175568)
Affinity DataIC50: 1nMAssay Description:Inhibition of ATM in human MCF7 cells using etoposide as substrate incubated for 1 hr by Cell Western assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Hubei Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50594889(CHEMBL5175568)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
In DepthDetails