BDBM50594520 CHEMBL5194845

SMILES OC(=O)C1(CCN(CC1)C(=O)C=C)c1ccccc1

InChI Key InChIKey=HAXNHVLKQBGHQG-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50594520   

TargetHistone-lysine N-methyltransferase 2A(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50594520(CHEMBL5194845)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of GST-tagged human MLL1 (1147 to 1203 residues) expressed in Escherichia coli BL21 cells incubated for 30 mins by fluorescence polarizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMethylcytosine dioxygenase TET1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50594520(CHEMBL5194845)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of GST-tagged human TET1 (583 to 633 residues) expressed in Escherichia coli BL21 cells incubated for 30 mins by fluorescence polarization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMethylcytosine dioxygenase TET3(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50594520(CHEMBL5194845)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of GST-tagged human TET3 (49 to 68 residues) expressed in Escherichia coli BL21 cell incubated for 30 mins by fluorescence polarization as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetLysine-specific demethylase 2A(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50594520(CHEMBL5194845)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of GST-tagged human KDM2A (562 to 618 residues) expressed in Escherichia coli BL21 cells incubated for 30 mins by fluorescence polarizatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetLysine-specific demethylase 2B(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50594520(CHEMBL5194845)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of GST-tagged human KDM2B (604 to 660 residues) expressed in Escherichia coli BL21 cells incubated for 30 mins by fluorescence polarizatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCXXC-type zinc finger protein 4(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50594520(CHEMBL5194845)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of GST-tagged human IDAX (130 to 181 residues) expressed in Escherichia coli BL21 cells incubated for 30 mins by fluorescence polarization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetF-box/LRR-repeat protein 19(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50594520(CHEMBL5194845)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of GST-tagged human FBXL19 (31 to 86 residues) expressed in Escherichia coli BL21 cells incubated for 30 mins by fluorescence polarization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCXXC-type zinc finger protein 5(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50594520(CHEMBL5194845)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of GST-tagged human CXXC5 (255 to 305 residues) expressed in Escherichia coli BL21 cells incubated for 30 mins by fluorescence polarizatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed