BDBM50594087 CHEMBL5189687

SMILES COc1cc2nc(NCCCN(C)C)nc(N(C)C3CCN(Cc4ccccc4)CC3)c2cc1OC

InChI Key InChIKey=LTIMUTHHZPKOSE-UHFFFAOYSA-N

Data  2 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50594087   

TargetREST corepressor 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50594087(CHEMBL5189687)
Affinity DataKd:  356nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetREST corepressor 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50594087(CHEMBL5189687)
Affinity DataKi:  569nMAssay Description:Inhibition of human LSD1/CoREST using histone H3 peptide as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50594087(CHEMBL5189687)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of G9a (unknown origin) assessed as reduction in substrate methylation using histone H3 and SAM as substrate measured after 15 to 60 mins ...More data for this Ligand-Target Pair
In DepthDetails
PubMed