BDBM50594012 CHEMBL5191676

SMILES CC#Cc1ccc2c(nc(CSc3ncccn3)[nH]c2=O)c1C

InChI Key InChIKey=VRECINGNBPANGK-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50594012   

TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50594012(CHEMBL5191676)
Affinity DataIC50: 14nMAssay Description:Inhibition of human full length GFP-tagged PARP11 in human HeLa cells incubated for 3 hrs by chemiluminescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50594012(CHEMBL5191676)
Affinity DataIC50: 9.28E+3nMAssay Description:Inhibition of PARP10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50594012(CHEMBL5191676)
Affinity DataIC50: 2.86E+3nMAssay Description:Inhibition of PARP14 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50594012(CHEMBL5191676)
Affinity DataIC50: 14nMAssay Description:Inhibition of PARP11 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50594012(CHEMBL5191676)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50594012(CHEMBL5191676)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP3(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50594012(CHEMBL5191676)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PARP3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50594012(CHEMBL5191676)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of TNKS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP15(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50594012(CHEMBL5191676)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PARP15 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50594012(CHEMBL5191676)
Affinity DataIC50: 14nMAssay Description:Inhibition of human full length PARP11 expressed in Escherichia coli BL21 (DE3) competent cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details Article
PubMed