BDBM50594010 CHEMBL5200358

SMILES Fc1ccccc1COc1ccc2c(c1)c(=O)[nH][nH]c2=O

InChI Key InChIKey=GJJIICZAOJXOEJ-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50594010   

TargetProtein mono-ADP-ribosyltransferase PARP10(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50594010(CHEMBL5200358)
Affinity DataIC50: 150nMAssay Description:Inhibition of human PARP-10 using NAD+ as substrate incubated for 10 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50594010(CHEMBL5200358)
Affinity DataIC50: 151nMAssay Description:Inhibition of human PARP-10 using NAD+ as substrate incubated for 10 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP15(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50594010(CHEMBL5200358)
Affinity DataIC50: 370nMAssay Description:Inhibition of human N-terminal 6His-tagged PARP15 (460 to 656 residues) expressed in Escherichia coli Rosetta2 (DE3) cells using NAD+ as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP15(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50594010(CHEMBL5200358)
Affinity DataIC50: 363nMAssay Description:Inhibition of human N-terminal 6His-tagged PARP15 (460 to 656 residues) expressed in Escherichia coli Rosetta2 (DE3) cells using NAD+ as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50594010(CHEMBL5200358)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PARP14 using NAD+ as substrate incubated for 10 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50594010(CHEMBL5200358)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PARP2 using NAD+ as substrate incubated for 10 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50594010(CHEMBL5200358)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human N-terminal 6His-tagged TNKS2 (1030 to 1317 residues) expressed in Escherichia coli Rosetta2 (DE3) cells using NAD+ as substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50594010(CHEMBL5200358)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PARP-1 using NAD+ as substrate incubated for 10 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP3(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50594010(CHEMBL5200358)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PARP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP4(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50594010(CHEMBL5200358)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PARP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50594010(CHEMBL5200358)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human TNKS1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP12(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50594010(CHEMBL5200358)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PARP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP16(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50594010(CHEMBL5200358)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PARP16More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed