BDBM50592853 CHEMBL5176252

SMILES OC(=O)CCNC(=O)c1ccc(cc1)-c1cc(n[nH]1)-c1ccc(O)c(c1)C(O)=O

InChI Key InChIKey=TXOQSJCSYHLIDK-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50592853   

TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50592853(CHEMBL5176252)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of recombinant human Sirt5 incubated for 1 hr by FLUOR DE LYS fluorometric microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50592853(CHEMBL5176252)
Affinity DataEC50:  2.57E+4nMAssay Description:Binding affinity to Sirt5 in human MCF7 cell lysate by pull down assay based LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNucleoside diphosphate kinase, mitochondrial(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50592853(CHEMBL5176252)
Affinity DataEC50:  1.45E+4nMAssay Description:Binding affinity to NME4 in human MCF7 cell lysate by pull down assay based LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGlutaryl-CoA dehydrogenase, mitochondrial(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50592853(CHEMBL5176252)
Affinity DataEC50:  5.02E+4nMAssay Description:Binding affinity to GCDH in human MCF7 cell lysate by pull down assay based LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed