BDBM50592249 CHEMBL5191395

SMILES COc1ccc2sc(cc2c1)C(=O)N(C)Cc1cc(F)cc(F)c1

InChI Key InChIKey=FLWYCOJREJRWLJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50592249   

TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592249(CHEMBL5191395)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant GST-tagged Clk1 (129 to 484 residues) expressed in Escherichia coli expression system using GRSRSRSRSRSRSRSR peptide ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592249(CHEMBL5191395)
Affinity DataIC50: 125nMAssay Description:Inhibition of human recombinant GST-tagged Clk2 expressed in Baculovirus expression system using GRSRSRSRSRSRSRSR peptide as substrate in presence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592249(CHEMBL5191395)
Affinity DataIC50: 355nMAssay Description:Inhibition of human recombinant GST tagged full length DYRK1A expressed in Baculovirus expression system using GRSRSRSRSRSRSRSR peptide as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50592249(CHEMBL5191395)
Affinity DataIC50: 13nMAssay Description:Inhibition of human CLK1 using GRSRSRSRSRSRSRS as substrate incubated for 15 mins in presence of ATP by gamma32P-ATP based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed