BDBM50591915 CHEMBL2130955

SMILES FC(F)(F)c1ccc(cc1)-c1cc(=O)c2ccccc2o1

InChI Key InChIKey=XISMXQJXDBDZSJ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50591915   

TargetCytochrome P450 4B1(Human)
University of Wuppertal

Curated by ChEMBL
LigandPNGBDBM50591915(CHEMBL2130955)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of CYP450 in human liver microsomes assessed as inhibition of 20-HETE formation in presence of arachidonic acid and NADPH by multi-enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCytochrome P450 4B1(Human)
University of Wuppertal

Curated by ChEMBL
LigandPNGBDBM50591915(CHEMBL2130955)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of CYP450 in human liver microsomes assessed as inhibition of 20-HETE formation in presence of arachidonic acid and NADPH by multi-enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCytochrome P450 4F2(Human)
University of Wuppertal

Curated by ChEMBL
LigandPNGBDBM50591915(CHEMBL2130955)
Affinity DataIC50: 760nMAssay Description:Inhibition of recombinant human CYP4F2 expressed in baculovirus-infected insect cells in presence of arachidonic acid and NADPH incubated for 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCytochrome P450 4F2(Human)
University of Wuppertal

Curated by ChEMBL
LigandPNGBDBM50591915(CHEMBL2130955)
Affinity DataIC50: 870nMAssay Description:Inhibition of recombinant human CYP4F2 expressed in baculovirus-infected insect cells in presence of arachidonic acid and NADPH incubated for 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCytochrome P450 4A11(Human)
University of Wuppertal

Curated by ChEMBL
LigandPNGBDBM50591915(CHEMBL2130955)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human CYP4A11 expressed in baculovirus-infected insect cells in presence of arachidonic acid and NADPH incubated for 15 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCytochrome P450 2J2(Human)
University of Wuppertal

Curated by ChEMBL
LigandPNGBDBM50591915(CHEMBL2130955)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human CYP2J2 expressed in baculovirus-infected insect cells in presence of arachidonic acid and NADPH incubated for 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCytochrome P450 4B1(Human)
University of Wuppertal

Curated by ChEMBL
LigandPNGBDBM50591915(CHEMBL2130955)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CYP450 in human HCT-116 cells assessed as 20-HETE formation in presence of arachidonic acid incubated for 15 mins by multi-enzyme assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCytochrome P450 4B1(Human)
University of Wuppertal

Curated by ChEMBL
LigandPNGBDBM50591915(CHEMBL2130955)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of CYP450 in human HCT-116 cells assessed as 20-HETE formation in presence of arachidonic acid incubated for 15 mins by multi-enzyme assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed