BDBM50591422 CHEMBL5175689

SMILES NC(=N)c1ccc(CNC(=O)c2cnn(Cc3ccccc3)c2)cc1

InChI Key InChIKey=SAVNTVHVERKVOD-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50591422   

TargetPlasma kallikrein(Human)
Kalvista Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50591422(CHEMBL5175689)
Affinity DataIC50: 62nMAssay Description:Inhibition of human plasma kallikrein using H-D-Pro-Phe-Arg-AFC as flurogenic substrate preincubated for 5 mins followed by substrate addition by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetPlasma kallikrein(Human)
Kalvista Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50591422(CHEMBL5175689)
Affinity DataIC50: 90nMAssay Description:Inhibition of plasma kallikrein (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPlasminogen(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50591422(CHEMBL5175689)
Affinity DataIC50: 10nMAssay Description:Inhibition of plasmin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProthrombin(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50591422(CHEMBL5175689)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCoagulation factor X(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50591422(CHEMBL5175689)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of fXa (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50591422(CHEMBL5175689)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of fXIa (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCoagulation factor XII(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50591422(CHEMBL5175689)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of fXIIa (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed