BDBM50591338 CHEMBL5203245::US20240182406, Example 9
SMILES FC1(CC1)C(=O)N1CCC(CC1)NC(=O)NC12CC3CC(Cl)(CC(C1)c1ccccc31)C2
InChI Key InChIKey=WHFWYHDLWCPIQQ-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50591338
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant human sEH using Nonfluorescent Cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl] carbonate as subs...More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of mouse sEH in using using Nonfluorescent Cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl] carbonate as substra...More data for this Ligand-Target Pair
Affinity DataIC50: 780nMAssay Description:Inhibition of human recombinant CYP2C19 using 3-cyano-7-ethoxycoumarin as a substrate preincubated for 5 mins followed by substrate addition by fluor...More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair