BDBM50591330 CHEMBL5197431::US20240182406, Example C11

SMILES CC(C)S(=O)(=O)N1CCC(CC1)NC(=O)NC12CC3CC(C)(CC(C1)c1ccccc31)C2

InChI Key InChIKey=KQKQYYXJYKFIRK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50591330   

TargetBifunctional epoxide hydrolase 2(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50591330(CHEMBL5197431 | US20240182406, Example C11)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant human sEH using Nonfluorescent Cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl] carbonate as subs...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50591330(CHEMBL5197431 | US20240182406, Example C11)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of mouse sEH in using using Nonfluorescent Cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl] carbonate as substra...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetEpoxide hydrolase 1(Human)
Universitat De Barcelona

US Patent
LigandPNGBDBM50591330(CHEMBL5197431 | US20240182406, Example C11)
Affinity DataIC50: 0.400nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In DepthDetails
US Patent