BDBM50591329 CHEMBL5179393::US20240182406, Example C7

SMILES CC12CC3CC(CC(C1)c1ccccc31)(C2)NC(=O)NC1CCN(CC1)C(=O)C1CCOCC1

InChI Key InChIKey=TYPYJBHGRSATKF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50591329   

TargetBifunctional epoxide hydrolase 2(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50591329(CHEMBL5179393 | US20240182406, Example C7)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human sEH using Nonfluorescent Cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl] carbonate as subs...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50591329(CHEMBL5179393 | US20240182406, Example C7)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of mouse sEH in using using Nonfluorescent Cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl] carbonate as substra...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetEpoxide hydrolase 1(Human)
Universitat De Barcelona

US Patent
LigandPNGBDBM50591329(CHEMBL5179393 | US20240182406, Example C7)
Affinity DataIC50: 1nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In DepthDetails
US Patent