BDBM50591046 CHEMBL5202342

SMILES Brc1nn(-c2ccc3ncccc3c2)c2nc(Nc3cnn(c3)C3CCNCC3)ncc12

InChI Key InChIKey=ISJDMEVRUNCZJN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50591046   

TargeteIF-2-alpha kinase GCN2(Human)
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50591046(CHEMBL5202342)
Affinity DataIC50: 3nMAssay Description:Inhibition of GCN2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Rapt Therapeutics

Curated by ChEMBL
LigandPNGBDBM50591046(CHEMBL5202342)
Affinity DataIC50: 610nMAssay Description:Inhibition of GCN2 in human SK-OV-3 cells assessed as reduction in phosphorylation of eIF2alpha by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed