BDBM50591031 CHEMBL5202450

SMILES COc1ccc(nn1)C#CCN(C(=O)Cc1ncc(cc1C(F)(F)F)C(F)(F)F)c1ccc(F)cc1

InChI Key InChIKey=MHYSOFBQLPMQEU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50591031   

TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandPNGBDBM50591031(CHEMBL5202450)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed