BDBM50591026 CHEMBL5197173

SMILES Fc1ccc(cc1)N(CC#Cc1cnn(c1)C1CNC1)C(=O)Cc1ncc(cc1C(F)(F)F)C(F)(F)F

InChI Key InChIKey=GBXMTWFYZDBZJF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50591026   

TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandPNGBDBM50591026(CHEMBL5197173)
Affinity DataIC50: 0.75nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed