BDBM50591020 CHEMBL5195161

SMILES FC(F)(F)c1ccc(CC(=O)N(CC#Cc2ccccn2)c2ccccc2)c(c1)C(F)(F)F

InChI Key InChIKey=QUDLMLJWGPEBHA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50591020   

TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandPNGBDBM50591020(CHEMBL5195161)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed