BDBM50590782 CHEMBL5208375

SMILES CCC(=O)N(Cc1ccc(F)cc1)C1CCN(CCc2ccccc2)CC1

InChI Key InChIKey=XXDSKBHNBRCBID-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50590782   

TargetMu-type opioid receptor(Human)
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM50590782(CHEMBL5208375)
Affinity DataEC50:  231nMAssay Description:Partial agonist activity at human MOR expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 45 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM50590782(CHEMBL5208375)
Affinity DataKi:  24nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM50590782(CHEMBL5208375)
Affinity DataKi:  224nMAssay Description:Displacement of [3H]-DAMGO from human MOR expressed in CHO-K1 cell membranes incubated for 90 mins measured by MicroBeta scintillation counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM50590782(CHEMBL5208375)
Affinity DataKi:  670nMAssay Description:Binding affinity to sigma2 receptor (unknown origin) measured by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed