BDBM50590419 CHEMBL5192637

SMILES C[C@@H](N1CCC(CC1)C(=O)NCc1cc(F)cc(NC(C)=O)c1)c1cccc2ccccc12

InChI Key InChIKey=NMLHDTHHBGXPOE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50590419   

TargetReplicase polyprotein 1ab(2019-nCoV)
Mazandaran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50590419(CHEMBL5192637)
Affinity DataIC50: 1.76E+3nMAssay Description:Inhibition of full-length SARS-CoV-2 PLpro expressed in Escherichia coli BL21(DE3) using HCC-RLRGG-NH(CH2)4NH-DABCYL probe as substrate incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Mazandaran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50590419(CHEMBL5192637)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of full-length SARS-CoV-2 PLpro expressed in Escherichia coli BL21(DE3) using Ub-Rho as substrate incubated for 5 mins by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed