BDBM50590022 CHEMBL5175444

SMILES [H][C@@]12CCCN1C(=O)[C@H](Cc1c[nH]c3ccccc13)NC(=O)[C@H](CCCNC(N)=N)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@]([H])(NC(=O)[C@H](CSCc1cccc(CSC[C@H](NC(=O)[C@@]([H])(NC2=O)[C@@H](C)CC)C(N)=O)c1)NC(C)=O)[C@@H](C)O

InChI Key InChIKey=QXPVZJDKFVQDGO-UHFFFAOYSA-N

Data  3 KI  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50590022   

TargetMelanocyte-stimulating hormone receptor(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50590022(CHEMBL5175444)
Affinity DataEC50:  3nMAssay Description:Agonist activity at human MC1R expressed in HEK2936E cells assessed as cAMP production in presence of IBMX by time resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMelanocortin receptor 3(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50590022(CHEMBL5175444)
Affinity DataEC50:  195nMAssay Description:Agonist activity at human MC3R expressed in HEK2936E cells assessed as cAMP production in presence of IBMX by time resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMelanocortin receptor 4(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50590022(CHEMBL5175444)
Affinity DataEC50:  302nMAssay Description:Antagonist activity at human MC4R expressed in HEK2936E cells assessed as cAMP production in presence of IBMX by time resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMelanocortin receptor 5(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50590022(CHEMBL5175444)
Affinity DataIC50: 1.78E+4nMAssay Description:Agonist activity at human MC5R expressed in HEK2936E cells assessed as cAMP production in presence of IBMX by time resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50590022(CHEMBL5175444)
Affinity DataKi:  110nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in HEK2936E cell membrane measured after 16 to 23 hrs by 1450 microbeta trilux scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMelanocortin receptor 4(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50590022(CHEMBL5175444)
Affinity DataKi:  1.29E+3nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC4R expressed in HEK2936E cell membrane measured after 16 to 23 hrs by 1450 microbeta trilux scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMelanocortin receptor 3(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50590022(CHEMBL5175444)
Affinity DataKi:  9.12E+3nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC3R expressed in HEK2936E cell membrane measured after 16 to 23 hrs by 1450 microbeta trilux scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed