BDBM50589721 CHEMBL5177099::US11760752, Compound 12

SMILES Cc1cc(Oc2ccc(Cn3nc4ccc(Cl)cc4c3C(O)=O)cc2)cc(C)c1Cl

InChI Key InChIKey=VSHOUNMVUKATSK-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50589721   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50589721(CHEMBL5177099 | US11760752, Compound 12)
Affinity DataKi:  2.36E+3nMAssay Description:Inhibition of MCL-1 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50589721(CHEMBL5177099 | US11760752, Compound 12)
Affinity DataKi:  2.36E+3nMAssay Description:The fluorescence polarization assays were performed in 96 well polypropylene F-bottom black microplates (Greiner Bio-One) with a final volume of 100 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
Go to US Patent