BDBM50588339 CHEMBL5187612

SMILES Cc1cccc(c1)C(=O)N1CCC2(CCNCC2)CC1

InChI Key InChIKey=FRKWUXZCSLOPIC-UHFFFAOYSA-N

Data  6 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50588339   

TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/delta(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588339(CHEMBL5187612)
Affinity DataIC50: 4.90E+3nMAssay Description:Antagonist activity at human alpha1beta2delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-1/delta(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588339(CHEMBL5187612)
Affinity DataIC50: 182nMAssay Description:Antagonist activity at human alpha4beta1delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588339(CHEMBL5187612)
Affinity DataIC50: 2.19E+3nMAssay Description:Antagonist activity at human alpha1beta2gamma2 GABAA receptor expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588339(CHEMBL5187612)
Affinity DataIC50: 7.41E+3nMAssay Description:Antagonist activity at human alpha2beta2gamma2 GABAA receptor expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588339(CHEMBL5187612)
Affinity DataIC50: 501nMAssay Description:Antagonist activity at human alpha3beta2gamma2 GABAA receptor expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588339(CHEMBL5187612)
Affinity DataIC50: 537nMAssay Description:Antagonist activity at human alpha5beta2gamma2 GABAA receptor expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-1/delta(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588339(CHEMBL5187612)
Affinity DataKi:  195nMAssay Description:Antagonist activity at human alpha4beta1delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588339(CHEMBL5187612)
Affinity DataKi:  540nMAssay Description:Antagonist activity at human alpha5beta2gamma2 GABAA receptor expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588339(CHEMBL5187612)
Affinity DataKi:  560nMAssay Description:Antagonist activity at human alpha3beta2gamma2 GABAA receptor expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588339(CHEMBL5187612)
Affinity DataKi:  2.18E+3nMAssay Description:Antagonist activity at human alpha1beta2gamma2 GABAA receptor expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/delta(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588339(CHEMBL5187612)
Affinity DataKi:  4.95E+3nMAssay Description:Antagonist activity at human alpha1beta2delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50588339(CHEMBL5187612)
Affinity DataKi:  7.56E+3nMAssay Description:Antagonist activity at human alpha2beta2gamma2 GABAA receptor expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed