BDBM50588315 CHEMBL5197309

SMILES Cc1cc(\C=C\C(=O)c2ccc(NC(=O)c3ccc(CN4C(=O)c5ccccc5C4=O)cc3)cc2)cc(C)c1C

InChI Key InChIKey=ZTAXUVNUGCXGDB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50588315   

TargetTubulin beta-3 chain(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588315(CHEMBL5197309)
Affinity DataIC50: 2.32E+3nMAssay Description:Inhibition of beta-tubulin polymerization in human MCF7 cells using TMB as substrate incubated for 2 hrs by spectrophotometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588315(CHEMBL5197309)
Affinity DataIC50: 220nMAssay Description:Inhibition of HDAC1 in human MCF7 cells using TMB as substrate incubated for 2 hrs by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588315(CHEMBL5197309)
Affinity DataIC50: 430nMAssay Description:Inhibition of HDAC2 in human MCF7 cells using TMB as substrate incubated for 2 hrs by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed