BDBM50588314 CHEMBL4542499

SMILES CC(C)(C)OC(=O)Nc1cccc(c1)C(=O)\C=C\c1ccc(\C=C\C(=O)NO)cc1

InChI Key InChIKey=XDLZZHYUUVQYDU-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50588314   

TargetHistone deacetylase 1(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50588314(CHEMBL4542499)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50588314(CHEMBL4542499)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50588314(CHEMBL4542499)
Affinity DataIC50: 11nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50588314(CHEMBL4542499)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50588314(CHEMBL4542499)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50588314(CHEMBL4542499)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using AMC-K(Ac)GL as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50588314(CHEMBL4542499)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using AMC-K(Ac)GL as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed