BDBM50587624 CHEMBL5182544

SMILES COc1cc(CCc2cc(n[nH]2)-c2nc3ccc(cc3[nH]2)N2C[C@H](C)N[C@H](C)C2)cc(OC)c1

InChI Key InChIKey=TUNDEPCHRSSRHC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50587624   

TargetFibroblast growth factor receptor 2(Human)
Celon Pharma

Curated by ChEMBL
LigandPNGBDBM50587624(CHEMBL5182544)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human FGFR2 (399 to 821 residues) expressed in baculovirus expression system using IGF-1Rtide peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 3(Human)
Celon Pharma

Curated by ChEMBL
LigandPNGBDBM50587624(CHEMBL5182544)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged FGFR3 (436 to 806 residues) expressed in baculovirus expression system using IGF-1Rtide peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Celon Pharma

Curated by ChEMBL
LigandPNGBDBM50587624(CHEMBL5182544)
Affinity DataIC50: 158nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human KDR (790 to 1356 residues) expressed in baculovirus expression system using IGF-1Rtide peptide ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Celon Pharma

Curated by ChEMBL
LigandPNGBDBM50587624(CHEMBL5182544)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human FGFR1 (398 to 822 residues) expressed in baculovirus expression system using IGF-1Rtide peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed