BDBM50587578 CHEMBL5091825
SMILES OCCOCc1cn(CCNc2nonc2\C(Nc2ccc(F)c(Br)c2)=N\O)nn1
InChI Key InChIKey=LFOXSTPPEXOYIT-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50587578
Affinity DataIC50: 28nMAssay Description:Inhibition of IDO1 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based ass...More data for this Ligand-Target Pair
Affinity DataIC50: 144nMAssay Description:Inhibition of IDO2 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based ass...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells assessed as reduction in kynurenine formation measured after 48 hrs by spectrophotometryMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of IDO1 in human HeLa cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of human IDO1More data for this Ligand-Target Pair
Affinity DataIC50: 144nMAssay Description:Inhibition of human IDO2More data for this Ligand-Target Pair