BDBM50586756 CHEMBL5089544

SMILES [H][C@]1(N=C(c2c(C)c(C)sc2-n2c(C)nnc12)c1ccc(Cl)cc1)[C@@H](CC)C(=O)OCCOCCOCCOCC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C)C(C)(C)C

InChI Key InChIKey=ILEZCIMECSOYKF-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50586756   

Targetvon Hippel-Lindau disease tumor suppressor(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50586756(CHEMBL5089544)
Affinity DataKd:  125nMAssay Description:Binding affinity to VHL (unknown origin) assessed as displacement of HIF-1alpha by binary binding competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed