BDBM50586498 CHEMBL5077332::US20240139189, Compound 22
SMILES CC1(CCN(CC1)Cc2cc(c(cc2F)N3CC(=O)NC4(C3)CCN(CC4)c5cc(ncn5)NC)F)C
InChI Key InChIKey=GYWOVBUGFWWSJR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50586498
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+3nMAssay Description:Thermal stabilization of recombinant METTL3 (354 to 580 residues) (unknown origin) expressed in HEK293T cells assessed as non-aggregated METTL3-ePL p...More data for this Ligand-Target Pair
Affinity DataEC50: 850nMAssay Description:Thermal stabilization of endogenously expressing full length METTL3 in human MOLM-13 cells assessed as stabilized METTL3 incubated for at 54 degC by ...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:No details are given in this patent.More data for this Ligand-Target Pair