BDBM50586494 CHEMBL5092187::US20240139189, Compound 16

SMILES CC1(C)CCN(Cc2ccc(cc2)N2CC(=O)NC3(CCN(CC3)c3cc(NC4CC4)ncn3)C2)CC1

InChI Key InChIKey=FWZHWNOKTFSSGE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50586494   

TargetN6-adenosine-methyltransferase catalytic subunit(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50586494(CHEMBL5092187 | US20240139189, Compound 16)
Affinity DataIC50: 84nMAssay Description:Inhibition of recombinant METLL3 (unknown origin) expressed in baculovirus infected Sf9 cells assessed as decrease in N6-methyladenosine level in oli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetN6-adenosine-methyltransferase non-catalytic subunit(Human)
University of Zurich

US Patent
LigandPNGBDBM50586494(CHEMBL5092187 | US20240139189, Compound 16)
Affinity DataIC50: 84nMAssay Description:No details are given in this patent.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
Go to US Patent