BDBM50586215 CHEMBL5080392

SMILES CC(=O)N1CCc2c(C1)sc1nc(SCC(=O)Nc3cc(Cl)ccc3C)n(Cc3ccco3)c(=O)c21

InChI Key InChIKey=WZPMLZHTAAYDCQ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50586215   

TargetBromodomain-containing protein 4(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50586215(CHEMBL5080392)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of BRD4-BD1 (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 4(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50586215(CHEMBL5080392)
Affinity DataIC50: 900nMAssay Description:Inhibition of BRD4-BD2 (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 3(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50586215(CHEMBL5080392)
Affinity DataIC50: 85nMAssay Description:Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 2(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50586215(CHEMBL5080392)
Affinity DataIC50: 120nMAssay Description:Inhibition of BRD2-BD2 (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 2(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50586215(CHEMBL5080392)
Affinity DataIC50: 2.60E+3nMAssay Description:Binding affinity to human partial length BRD2-BD2 (E348 to D455) expressed in bacterial system assessed as dissociation constant by BROMOscan methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 3(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50586215(CHEMBL5080392)
Affinity DataIC50: 325nMAssay Description:Binding affinity to human partial length BRD3-BD2 (G306 to P416) expressed in bacterial system assessed as dissociation constant by BROMOscan methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 4(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50586215(CHEMBL5080392)
Affinity DataIC50: 775nMAssay Description:Binding affinity to human partial length BRD4-BD2 (K333 to E460 residues) expressed in bacterial system assessed as dissociation constant by BROMOsca...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 3(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50586215(CHEMBL5080392)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of BRD3-BD1 domain (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed