BDBM50586141 CHEMBL5079068

SMILES CC(C)C[C@H](N)COc1ccc(cc1)-c1ccncc1

InChI Key InChIKey=FRILLJZXUHFGBE-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50586141   

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50586141(CHEMBL5079068)
Affinity DataIC50: 49nMAssay Description:Inhibition of GST-Xa tagged human AAK1 (30 to 330 residues) expresssed in bacteria using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50586141(CHEMBL5079068)
Affinity DataIC50: 48nMAssay Description:Inhibition of AKK1 in HEK293F cells assessed as reduction in phospho mu2 formation incubated for 3 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50586141(CHEMBL5079068)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) using BFC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50586141(CHEMBL5079068)
Affinity DataIC50: 49nMAssay Description:Inhibition of AAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50586141(CHEMBL5079068)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50586141(CHEMBL5079068)
Affinity DataIC50: 48nMAssay Description:Inhibition of AAK1 expressed in human HEK293K cellsMore data for this Ligand-Target Pair
In DepthDetails
PubMed