BDBM50585932 CHEMBL5081574

SMILES Cc1c(C)c(=O)oc2cc(OCC3CCN(CCCC(F)F)CC3)ccc12

InChI Key InChIKey=NQNJDDJLRMICLQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50585932   

TargetAmine oxidase [flavin-containing] B(Human)
University of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585932(CHEMBL5081574)
Affinity DataIC50: 530nMAssay Description:Inhibition of human recombinant MAO-B expressed in supersomes assessed as inhibition of 4-hydroxyquinoline formation using kynuramine as substrate by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585932(CHEMBL5081574)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant AChE by Ellman's spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50585932(CHEMBL5081574)
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant CYP3A4 expressed in baculosomes by fluorescent homogenous assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed