BDBM50585192 CHEMBL5088682

SMILES NS(=O)(=O)c1ccc(CNc2nc(Nc3cccc(NC(=O)N4CCCC4)c3)ncc2C2CC2)cc1

InChI Key InChIKey=YEEWXIVVPABJAB-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50585192   

TargetHigh affinity nerve growth factor receptor(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50585192(CHEMBL5088682)
Affinity DataIC50: 477nMAssay Description:Inhibition of human TrkA (440 to end residues) using KKKSPGEYVNIEFG as substrate measured after 40 mins in presence of [gamma33P]ATP by scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 17A(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50585192(CHEMBL5088682)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of tracer K9 from NLuc fused DRAK1 (unknown origin) expressed in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetMAP/microtubule affinity-regulating kinase 3(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50585192(CHEMBL5088682)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of tracer K9 from NLuc fused MARK3 (unknown origin) expressed in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetMAP/microtubule affinity-regulating kinase 4(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50585192(CHEMBL5088682)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of tracer K5 from NLuc fused MARK4 (unknown origin) expressed in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase TBK1(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50585192(CHEMBL5088682)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of tracer K5 from NLuc fused TBK1 (unknown origin) expressed in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase TBK1(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50585192(CHEMBL5088682)
Affinity DataIC50: 128nMAssay Description:Inhibition of human TTBK1 (1 to 479 residues) using Casein as substrate measured after 40 mins in presence of [gamma33P]ATP by scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50585192(CHEMBL5088682)
Affinity DataIC50: 2.92E+3nMAssay Description:Inhibition of 1recombinant human BMPR2 (172 to 734 residues) using myelin basic protein as substrate incubated for 120 mins in presence of [gamma-33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed