BDBM50585092 CHEMBL5087577

SMILES CN1CCN(CCNc2nccc(n2)-c2c(nc3sccn23)-c2cccc(O)c2)S1(=O)=O

InChI Key InChIKey=WBOYUDKCKRWVNR-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50585092   

TargetSerine/threonine-protein kinase B-raf(Human)
National Research Centre (Nrc)

Curated by ChEMBL
LigandPNGBDBM50585092(CHEMBL5087577)
Affinity DataIC50: 2nMAssay Description:Inhibition of human wild type BRAF using myelin basic protein as substrate in presence of [gamma-33P]ATP incubated for 40 mins by scintillation count...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
National Research Centre (Nrc)

Curated by ChEMBL
LigandPNGBDBM50585092(CHEMBL5087577)
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of human BRAF V600E mutant using myelin basic protein as substrate in presence of [gamma-33P]ATP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
National Research Centre (Nrc)

Curated by ChEMBL
LigandPNGBDBM50585092(CHEMBL5087577)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human wild type CRAF using myelin basic protein as substrate in presence of [gamma-33P]ATP incubated for 40 mins by scintillation count...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
National Research Centre (Nrc)

Curated by ChEMBL
LigandPNGBDBM50585092(CHEMBL5087577)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of ABL1 (unknown origin) incubated for 1 hr by qPCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase/endoribonuclease IRE1(Human)
National Research Centre (Nrc)

Curated by ChEMBL
LigandPNGBDBM50585092(CHEMBL5087577)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of ERN1 (unknown origin) incubated for 1 hr by qPCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
National Research Centre (Nrc)

Curated by ChEMBL
LigandPNGBDBM50585092(CHEMBL5087577)
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of FGFR1 (unknown origin) incubated for 1 hr by qPCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
National Research Centre (Nrc)

Curated by ChEMBL
LigandPNGBDBM50585092(CHEMBL5087577)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of FLT3 (unknown origin) incubated for 1 hr by qPCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
National Research Centre (Nrc)

Curated by ChEMBL
LigandPNGBDBM50585092(CHEMBL5087577)
Affinity DataIC50: 3.78E+3nMAssay Description:Inhibition of HIPK1 (unknown origin) incubated for 1 hr by qPCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
National Research Centre (Nrc)

Curated by ChEMBL
LigandPNGBDBM50585092(CHEMBL5087577)
Affinity DataIC50: 910nMAssay Description:Inhibition of MAPK8 (unknown origin) incubated for 1 hr by qPCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 11(Human)
National Research Centre (Nrc)

Curated by ChEMBL
LigandPNGBDBM50585092(CHEMBL5087577)
Affinity DataIC50: 820nMAssay Description:Inhibition of MAPK11 (unknown origin) incubated for 1 hr by qPCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
National Research Centre (Nrc)

Curated by ChEMBL
LigandPNGBDBM50585092(CHEMBL5087577)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of MAPK14 (unknown origin) incubated for 1 hr by qPCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 20(Human)
National Research Centre (Nrc)

Curated by ChEMBL
LigandPNGBDBM50585092(CHEMBL5087577)
Affinity DataIC50: 9.01E+3nMAssay Description:Inhibition of ZAK (unknown origin) incubated for 1 hr by qPCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
National Research Centre (Nrc)

Curated by ChEMBL
LigandPNGBDBM50585092(CHEMBL5087577)
Affinity DataIC50: 8.04E+3nMAssay Description:Inhibition of NTRK2 (unknown origin) incubated for 1 hr by qPCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed