BDBM50584007 CHEMBL5083414

SMILES NC(=O)[C@@H]1C[C@H](F)CN1Cc1ccc(OCc2cccc(F)c2)cc1

InChI Key InChIKey=LQAIMOYHJBOUSX-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50584007   

TargetAmine oxidase [flavin-containing] A(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584007(CHEMBL5083414)
Affinity DataIC50: 4.64E+4nMAssay Description:Inhibition of recombinant human MAO-A expressed in Sf9 cells preincubated for 15 min followed by addition of p-tyramine and measured after 60 min by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584007(CHEMBL5083414)
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human MAO-B expressed in Sf9 cells preincubated for 15 min followed by addition of benzylamine and measured after 60 min by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584007(CHEMBL5083414)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human CYP1A2 preincubated for 10 min followed by addition of NADPH and measured after 10 min by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584007(CHEMBL5083414)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human CYP2B6 preincubated for 10 min followed by addition of NADPH and measured after 10 min by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584007(CHEMBL5083414)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human CYP2C8 preincubated for 10 min followed by addition of NADPH and measured after 45 min by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584007(CHEMBL5083414)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human CYP2C9 preincubated for 10 min followed by addition of NADPH and measured after 10 min by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584007(CHEMBL5083414)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human CYP2C19 preincubated for 10 min followed by addition of NADPH and measured after 45 min by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584007(CHEMBL5083414)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human CYP2D6 preincubated for 10 min followed by addition of NADPH and measured after 10 min by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584007(CHEMBL5083414)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human CYP3A4 preincubated for 10 min followed by addition of NADPH and measured after 5 min by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCytochrome P450 3A5(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584007(CHEMBL5083414)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human CYP3A5 preincubated for 10 min followed by addition of NADPH and measured after 5 min by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50584007(CHEMBL5083414)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Patch Clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed