BDBM50583916 CHEMBL4786320

SMILES FC(F)(F)c1cnc(N[C@H]2CCCNC2)nc1-c1c[nH]c2ccccc12

InChI Key InChIKey=QVBVFLKFEISMLZ-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50583916   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Syros Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50583916(CHEMBL4786320)
Affinity DataIC50: 42nMAssay Description:Inhibition of CDK2/cyclin E1 (unknown origin) using 5-FAM-labeled peptide as substrate in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50583916(CHEMBL4786320)
Affinity DataKd:  0.150nMAssay Description:Binding affinity to full length CDK7 (1 to 346 residues) /N-terminal TEV cleavable 6His tagged full length cyclinH (1 to 323 residues) (unknown origi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Syros Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50583916(CHEMBL4786320)
Affinity DataIC50: 21nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) using 5-FAM-labeled peptide as substrate in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 12(Human)
Syros Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50583916(CHEMBL4786320)
Affinity DataIC50: 24nMAssay Description:Inhibition of CDK12/cyclin K (unknown origin) using 5-FAM-labeled peptide as substrate in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed