BDBM50583211 CHEMBL5078247

SMILES Cc1cc(C)n(n1)-c1nc(C)cc(Nc2ccc(F)c(Cl)c2)n1

InChI Key InChIKey=LBSKGGZCJBHZET-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50583211   

TargetSmall conductance calcium-activated potassium channel protein 2(Rat)
Chapman University School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50583211(CHEMBL5078247)
Affinity DataEC50:  990nMAssay Description:Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Human)
Chapman University School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50583211(CHEMBL5078247)
Affinity DataEC50:  190nMAssay Description:Potentiation of human KCa2.3 expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology relative ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSmall conductance calcium-activated potassium channel protein 2(Rat)
Chapman University School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50583211(CHEMBL5078247)
Affinity DataEC50:  110nMAssay Description:Potentiation of rat KCa2.2a expressed in HEK293 cells assessed as increase in calcium response at -90 mV holding potential measured at 1 to 2 days by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed