BDBM50582461 CHEMBL5093633

SMILES Cc1ccc(c(F)c1)-c1cc(\C=C\c2ccc(cc2)C(=O)NO)ccn1

InChI Key InChIKey=AYKITWJAPVHRAX-UHFFFAOYSA-N

Data  17 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50582461   

TargetLysine-specific histone demethylase 1A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50582461(CHEMBL5093633)
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50582461(CHEMBL5093633)
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of human LSD1 (unknown orgin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 6(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582461(CHEMBL5093633)
Affinity DataIC50: 15nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 2(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582461(CHEMBL5093633)
Affinity DataIC50: 400nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 1(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582461(CHEMBL5093633)
Affinity DataIC50: 370nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50582461(CHEMBL5093633)
Affinity DataKd:  240nMAssay Description:Binding affinity to LSD1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 6(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582461(CHEMBL5093633)
Affinity DataIC50: 15nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 2(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582461(CHEMBL5093633)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone deacetylase 1(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582461(CHEMBL5093633)
Affinity DataIC50: 370nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50582461(CHEMBL5093633)
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of recombinant LSD1 (157 to 852 residues) (unknown origin) expressed in Escherichia coli BL21 (DE) using H3K4me2 as substrate by amplex re...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 11(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582461(CHEMBL5093633)
Affinity DataIC50: 4.93E+3nMAssay Description:Inhibition of HDAC11 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition by fluorescence based mic...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582461(CHEMBL5093633)
Affinity DataIC50: 8.78E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition by fluorescence based micr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 2(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582461(CHEMBL5093633)
Affinity DataIC50: 404nMAssay Description:Inhibition of HDAC2 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition by fluorescence based micr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582461(CHEMBL5093633)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MAO-B by multimode plate reader assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582461(CHEMBL5093633)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MAO-A by multimode plate reader assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582461(CHEMBL5093633)
Affinity DataIC50: 15nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 5(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582461(CHEMBL5093633)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC5 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582461(CHEMBL5093633)
Affinity DataIC50: 370nMAssay Description:Inhibition of HDAC1 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed