BDBM50582460 CHEMBL5075694

SMILES COc1ccc(cc1)-c1cc(\C=C\c2ccc(cc2)C(=O)NO)ccn1

InChI Key InChIKey=HXSCYJUDKNTYLK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50582460   

TargetLysine-specific histone demethylase 1A(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582460(CHEMBL5075694)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of recombinant LSD1 (157 to 852 residues) (unknown origin) expressed in Escherichia coli BL21 (DE) using H3K4me2 as substrate by amplex re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582460(CHEMBL5075694)
Affinity DataIC50: 690nMAssay Description:Inhibition of HDAC1 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582460(CHEMBL5075694)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC5 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50582460(CHEMBL5075694)
Affinity DataIC50: 110nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed