BDBM50581956 CHEMBL5085088

SMILES CCCCn1c(=O)n(CCCNC(=O)c2ccc(cc2)S(O)(=O)=O)c2[nH]c(nc2c1=O)C12CCC(CC1)(CC2)C(=O)NCCCN=[N+]=[N-]

InChI Key InChIKey=YYGSISGTSGWHBY-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50581956   

TargetAdenosine receptor A1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50581956(CHEMBL5085088)
Affinity DataKi:  6nMAssay Description:Binding affinity to human Adenosine A1 receptor expressed in Flp-In-CHO cell membrane by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50581956(CHEMBL5085088)
Affinity DataKi:  88nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in Flp-In-CHO cell membrane assessed as inhibition of forskolin-stimulated cAMP accumula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50581956(CHEMBL5085088)
Affinity DataKi:  603nMAssay Description:Displacement of [3H] DPCPX from human A1 adenosine receptor expressed in Flp-In-CHO cell membrane incubated for 4 hrs by microbeta scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50581956(CHEMBL5085088)
Affinity DataKi:  605nMAssay Description:Displacement of [3H] DPCPX from human A1 adenosine receptor expressed in Flp-In-CHO cell membrane incubated for 4 hrs by microbeta scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed