BDBM50581665 CHEMBL5084571

SMILES COc1cc2nc(C)nc(N[C@H](C)c3cccc(c3)C(F)(F)F)c2cc1OC

InChI Key InChIKey=UWEJNKMEGIGAGY-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50581665   

TargetSon of sevenless homolog 1(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50581665(CHEMBL5084571)
Affinity DataKd:  104nMAssay Description:Binding affinity to SOS1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50581665(CHEMBL5084571)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed