BDBM50580964 CHEMBL5094423

SMILES CNC(=O)Nc1ccc2c(CC[C@@]22OC(=O)N(CC(=O)N3Cc4sccc4OC[C@H]3C3CC3)C2=O)c1

InChI Key InChIKey=ATLJVYAAMGQNOV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50580964   

TargetHistone acetyltransferase p300(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580964(CHEMBL5094423)
Affinity DataIC50: 4nMAssay Description:Inhibition of p300 (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCREB-binding protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580964(CHEMBL5094423)
Affinity DataIC50: 12nMAssay Description:Inhibition of CBP (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed