BDBM50580530 CHEMBL5092744
SMILES OC[C@@H](NCc1cc(Cl)c(OCc2cccc(c2Br)-c2ccccc2)cc1OCc1ccc2nonc2c1)C(O)=O
InChI Key InChIKey=OUHGBSZZOWVTDI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50580530
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as blockade activity incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.30nMAssay Description:Binding affinity to human PD-L1 assessed as dissociation constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: 375nMAssay Description:Inhibition of human PD-1/PD-L1 interaction in human Jurkat cells expressing PD-1/NFAT/Luc cocultured with CHO-K1 cells expressing PD-L1/aAPC assessed...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataKd: 3.30nMAssay Description:Binding affinity to human PD-1 assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair