BDBM50580323 CHEMBL5076580

SMILES OC(=O)c1cnc(SCc2ccccc2)[nH]c1=O

InChI Key InChIKey=FZQGMHMSZJMNOX-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50580323   

TargetHypoxia-inducible factor 1-alpha inhibitor(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50580323(CHEMBL5076580)
Affinity DataIC50: 2.02E+4nMAssay Description:Inhibition of human FIH using HLEVVKLLLEAGADVNAQDK-CONH2 as substrate preincubated for 15 mins followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 2A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50580323(CHEMBL5076580)
Affinity DataIC50: 6.72E+4nMAssay Description:Inhibition of human N-terminal His6-tagged KDM2A (M1 to P517 residues) expressed in insect cells using H3K36(Me2) as substrate preincubated for 15 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 3B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50580323(CHEMBL5076580)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human N-terminal His6-tagged KDM3B (L882 to S1761 residues) expressed in insect cells using H3K9(Me2) as substrate preincubated for 15 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50580323(CHEMBL5076580)
Affinity DataIC50: 2.46E+4nMAssay Description:Inhibition of human N-terminal His6-tagged KDM4A (M1 to L359 residues) expressed in Escherichia coli using H3K9(Me3) as substrate preincubated for 15...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4D(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50580323(CHEMBL5076580)
Affinity DataIC50: 3.47E+4nMAssay Description:Inhibition of human N-terminal His6-tagged KDM4D (M1 to G373 residues) expressed in Escherichia coli using H3K9(Me3) as substrate preincubated for 15...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 5B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50580323(CHEMBL5076580)
Affinity DataIC50: 8.48E+4nMAssay Description:Inhibition of human N-terminal His6-tagged KDM5B (L882 to S1761 residues) expressed in insect cells using H3K4(Me3) as substrate preincubated for 15 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 6B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50580323(CHEMBL5076580)
Affinity DataIC50: 7.46E+4nMAssay Description:Inhibition of human KDM6B (D1141 to R1641 residues) expressed in Escherichia coli using H3K27(Me3) as substrate preincubated for 15 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed