BDBM50579693 CHEMBL5092182

SMILES COc1ccc(cc1S(=O)(=O)Nc1cccc(NCCNC(=O)c2cccc(C)c2)c1)-c1csc(c1)C(=O)N(C)C

InChI Key InChIKey=VBXMNHVQADZGMH-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50579693   

TargetOrexin/Hypocretin receptor type 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50579693(CHEMBL5092182)
Affinity DataEC50:  1.33E+3nMAssay Description:Agonist activity at human OX1R stably expressed in CHO RD-HGA16 cells assessed as fluorescence changes measured after 30 mins by calcium mobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50579693(CHEMBL5092182)
Affinity DataEC50:  166nMAssay Description:Agonist activity at human OX2R stably expressed in CHO RD-HGA16 cells assessed as fluorescence changes measured after 30 mins by calcium mobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed