BDBM50579375 CHEMBL4858133

SMILES ONC(=O)c1ccc(CN2c3ccccc3Sc3ccccc23)nc1

InChI Key InChIKey=YKILUTGCNNQKON-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50579375   

TargetHistone deacetylase 6(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50579375(CHEMBL4858133)
Affinity DataIC50: 11nMAssay Description:Inhibition of human HDAC6 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50579375(CHEMBL4858133)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human HDAC6 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50579375(CHEMBL4858133)
Affinity DataIC50: 5.63E+3nMAssay Description:Inhibition of human HDAC4 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50579375(CHEMBL4858133)
Affinity DataIC50: 8.63E+3nMAssay Description:Inhibition of human HDAC10 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50579375(CHEMBL4858133)
Affinity DataIC50: 6.12E+3nMAssay Description:Inhibition of human HDAC8 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50579375(CHEMBL4858133)
Affinity DataIC50: 743nMAssay Description:Inhibition of human HDAC1 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50579375(CHEMBL4858133)
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of human HDAC2 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50579375(CHEMBL4858133)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human HDAC11 using fluorogenic substrate incubated for 1 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed