BDBM50579176 CHEMBL4854673

SMILES CS(=O)(=O)c1ccc(cc1)-c1ccc2c(ccnc2c1)-n1ccc2cnc(nc12)-c1cc(F)ccc1F

InChI Key InChIKey=AKOPAPJGZCKALV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50579176   

TargetTGF-beta receptor type-1(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50579176(CHEMBL4854673)
Affinity DataIC50: 283nMAssay Description:Inhibition of human TGFbeta receptor 1 in human HEK293 cells preincubated for 24 hrs followed by addition of TGFbeta1 and measured after 24 hrs by lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed