BDBM50579053 CHEMBL4868405

SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(CN3CCN(Cc4cccs4)CC3)c2o1

InChI Key InChIKey=RNPMZVGNPDWZAV-UHFFFAOYSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50579053   

TargetPoly [ADP-ribose] polymerase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50579053(CHEMBL4868405)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human full-length PARP-1 using biotinylated substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50579053(CHEMBL4868405)
Affinity DataIC50: 900nMAssay Description:Inhibition of recombinant human full-length PARP-2 using biotinylated substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50579053(CHEMBL4868405)
Affinity DataKd:  55nMAssay Description:Binding affinity to recombinant human PARP-1 by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50579053(CHEMBL4868405)
Affinity DataKd:  605nMAssay Description:Binding affinity to recombinant human PARP-2 by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed