BDBM50577487 CHEMBL4857145

SMILES Cc1ccc(s1)-c1nc(CCc2ccccc2)c(nc1C)-c1cccc(F)c1O

InChI Key InChIKey=YCTSZTFLLOJXER-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50577487   

TargetNuclear receptor subfamily 1 group I member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50577487(CHEMBL4857145)
Affinity DataEC50:  3.20E+3nMAssay Description:Activation of full length human PXR expressed in human HepG2 cells co-expressing luciferase of CYP3A4 promoter transcription assessed as increase of ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50577487(CHEMBL4857145)
Affinity DataIC50: 110nMAssay Description:Antagonist activity at human CaSR in human HEK293 cells measured after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed