BDBM50576850 CHEMBL4865552

SMILES [H][C@@]12Oc3cc(F)c(cc3CN1C(=O)O[C@H]2CNC(C)=O)-c1ccc(nc1)C#N

InChI Key InChIKey=BTKRYFYNWYZUAN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50576850   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50576850(CHEMBL4865552)
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by whole cell manual patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50576850(CHEMBL4865552)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of MAO-A (unknown origin) using kynuramine as substrate preincubated for 5 mins with substrate followed by enzyme addition and measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50576850(CHEMBL4865552)
Affinity DataIC50: 6.07E+3nMAssay Description:Inhibition of MAO-B (unknown origin) using kynuramine as substrate preincubated for 5 mins with substrate followed by enzyme addition and measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed